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KPV 10MG

KPV is a short tripeptide fragment (Lys-Pro-Val) derived from the hormone α-melanocyte-stimulating hormone (α-MSH). It is known primarily for its anti-inflammatory and immunomodulatory properties. Research has shown that KPV may help reduce inflammation in the gut, skin, and systemic tissues by downregulating pro-inflammatory cytokines and supporting barrier function. Because of these actions, it has been studied in models of inflammatory bowel disease, wound healing, and skin conditions. Its small size and stability make it attractive in research settings focused on recovery, healing, and immune balance.

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$50.00

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The information provided on this page is intended solely as a general summary. It does not encompass all potential research applications, handling procedures, safety precautions, interactions, or observed effects. These products are supplied strictly for laboratory and research purposes only. They are not intended for human consumption, medical use, veterinary use, or diagnostic purposes. This information must not be considered a substitute for professional expertise, judgment, or regulatory guidance.

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SEQUENCE/FORMULA

Sequence: Lys-Pro-Val
Molecular Formula: C17H31N5O4

MOLECULAR WEIGHT

369.46 g/mol

PUBCHEM CID

16132369

  • Studying its anti-inflammatory effects in gut health and inflammatory bowel disease models

  • Exploring its role in wound healing and tissue repair

  • Investigating its potential in dermatological conditions such as eczema and psoriasis

  • Researching its systemic immune-modulating properties

  • Derived from the α-MSH peptide, retaining potent anti-inflammatory activity

  • Inhibits production of pro-inflammatory cytokines (TNF-α, IL-6, IL-1β)

  • Enhances barrier integrity in epithelial and gut tissue

  • Supports wound healing by reducing oxidative stress and promoting cellular repair

  • Getting SJ. Melanocortin peptides and their receptors: new targets for anti-inflammatory therapy. Trends Pharmacol Sci. 2002;23(10):447–449.

  • Chen W, et al. Anti-inflammatory properties of the tripeptide KPV in intestinal epithelial cells. Inflamm Res. 2008;57(10):424–429.

  • Catania A, et al. The neuropeptide α-MSH controls inflammation. J Mol Med. 1999;77(7):617–626.