DSIP 5MG

Delta sleep-inducing peptide for neurological and sleep cycle research.

$55.00

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SEQUENCE/FORMULA

Sequence: Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu Molecular Formula: C35​H48​N10​O15​

MOLECULAR WEIGHT

848.8 g/mol

PUBCHEM CID

4635
  • Studying its role in promoting deeper, more restorative sleep
  • Investigating its potential to reduce feelings of stress and anxiety
  • Analyzing its ability to help normalize the body's natural sleep-wake cycle
  • Researching its potential to ease withdrawal symptoms
  • Exploring its protective effects on brain cells
  • The exact mechanisms of DSIP are complex and not fully elucidated, as it appears to act on multiple systems in the body and brain.
  • It readily crosses the blood-brain barrier and is believed to have a neuromodulatory effect, meaning it helps to regulate and normalize brain activity rather than acting as a direct sedative like traditional sleep medications.
  • Research suggests it may influence major neurotransmitter systems, including serotonin and GABA, which are critical for regulating sleep, mood, and stress.
  • It is considered a "stress-limiting" peptide, potentially by reducing the body's cortisol response to stress and exhibiting antioxidant activity in the brain.
  • Schoenenberger, G. A., & Monnier, M. (1977). Characterization of a delta-electroencephalogram(-sleep)-inducing peptide. Proceedings of the National Academy of Sciences, 74(3), 1282–1286.
  • Graf, M. V., & Kastin, A. J. (1984). Delta-sleep-inducing peptide (DSIP): a review. Neuroscience & Biobehavioral Reviews, 8(1), 83–93.
  • Sudakov, K. V., et al. (2001). Delta sleep-inducing peptide (DSIP): A tool for studying the systemic mechanisms of behavior. Journal of Physiology and Pharmacology, 52(2), 153-164.
  • Abba, J., et al. (2018). Delta sleep-inducing peptide (DSIP): A review of its hypnotic and stress-protective effects. Peptides, 104, 39-44.