SS-31 50MG
SS-31 (also known as Elamipretide) is a synthetic, mitochondria-targeted tetrapeptide designed to restore cellular energy production. Unlike standard antioxidants that simply neutralize free radicals, SS-31 penetrates deep into the mitochondria and binds to a specific lipid called cardiolipin. By stabilizing the structure of the inner mitochondrial membrane, it helps the “cellular power plants” run more efficiently, reduces the production of toxic oxidative stress, and improves the health of energy-demanding organs like the heart, brain, and kidneys.
Original price was: $125.00.$98.00Current price is: $98.00.
The information provided on this page is intended solely as a general summary. It does not encompass all potential research applications, handling procedures, safety precautions, interactions, or observed effects. These products are supplied strictly for laboratory and research purposes only. They are not intended for human consumption, medical use, veterinary use, or diagnostic purposes. This information must not be considered a substitute for professional expertise, judgment, or regulatory guidance.
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Brain Health: Research shows it protects neurons and improves memory in Alzheimer’s and Parkinson’s models by reducing brain inflammation.
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Heart Function: It is being studied to treat Heart Failure and Barth Syndrome by helping the heart pump more efficiently and reducing tissue scarring.
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Kidney Repair: Studies indicate it prevents "leaky" filters in the kidney, offering protection against Diabetic Kidney Disease and acute injuries.
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Muscle Recovery: Scientists use it to reverse Age-related muscle wasting, restoring exercise endurance and "youthful" energy levels in older muscle fibers.
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Vision Preservation: It is applied in research for Glaucoma and Macular Degeneration to shield eye cells from oxidative damage that leads to blindness.
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Selective Cardiolipin Binding: SS-31 specifically seeks out and binds to cardiolipin, a unique fat molecule found only in the inner lining of the mitochondria.
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Membrane Stabilization: By anchoring to cardiolipin, it helps maintain the curved, finger-like structure of the mitochondrial cristae, which is essential for efficient energy production.
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Supercomplex Assembly: It helps the cell's energy-making proteins group together into "supercomplexes," which allows electricity (electrons) to flow faster and with less waste.
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Peroxidase Inhibition: It prevents a protein called Cytochrome c from turning into a destructive enzyme that would otherwise damage the mitochondrial membrane during stress.
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Reduction of Energy "Leaks": By optimizing the energy flow, it stops the production of Reactive Oxygen Species (ROS)—the "smoke" or waste that causes inflammation and cellular aging.
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Discovery Paper (Szeto & Schiller, 2004): This is the foundational study that first identified SS-31. It proved that the peptide could pass through cell membranes and accumulate in mitochondria to stop "oxidative" damage.
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Mechanism Study (Journal of Biological Chemistry, 2004): Research by Zhao et al. that first demonstrated how SS-31 protects the heart and brain from "reperfusion injury"—the damage caused when blood flow returns to a starved organ.
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Cardiolipin Binding Review (Szeto, 2014): A major scientific review in the British Journal of Pharmacology that defined exactly how SS-31 works: by latching onto Cardiolipin to fix the internal structure of the mitochondria.
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Human Trial Results (MMPOWER Study): Published in journals like Neurology, this study represents the first successful human trial showing that SS-31 could improve walking distance and energy in patients with rare mitochondrial diseases.
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Muscle Aging Research (Aging Cell, 2017): A key reference showing that SS-31 can restore energy production in aging muscles, essentially making older muscle fibers function like younger ones during exercise.