FOLLISTATIN 344 1MG
Follistatin-344 is a glycoprotein that is researched for its ability to bind to and inhibit myostatin, a protein that limits muscle growth. By inhibiting myostatin, it is studied for its potential to promote muscle hypertrophy.
Original price was: $140.00.$110.00Current price is: $110.00.
The information provided on this page is intended solely as a general summary. It does not encompass all potential research applications, handling procedures, safety precautions, interactions, or observed effects. These products are supplied strictly for laboratory and research purposes only. They are not intended for human consumption, medical use, veterinary use, or diagnostic purposes. This information must not be considered a substitute for professional expertise, judgment, or regulatory guidance.
Money Back Guarantee
Guaranteed Quality
Fast Shipping
10+ Years Experience
Frequently Bought Together
SEQUENCE/FORMULA
MOLECULAR WEIGHT
PUBCHEM CID
- 128886981 (This ID corresponds to the human Follistatin protein).
- Investigating its primary function as a potent myostatin inhibitor
- Studying its effects on promoting significant muscle growth (hypertrophy)
- Analyzing its potential to prevent muscle wasting (atrophy) in various research models
- Researching its role in cellular differentiation and tissue repair
- Exploring its secondary effects on metabolism and fertility
- Follistatin is a secreted protein that acts as a powerful antagonist (inhibitor) of several proteins in the TGF-β superfamily.
- Its most well-known mechanism is the direct binding and neutralization of myostatin. Myostatin is a protein that acts as a negative regulator of muscle growth, essentially putting the "brakes" on how large muscles can get. By binding to myostatin, Follistatin prevents it from acting on its receptor, thereby "releasing the brakes" and allowing for significant muscle growth.
- It also binds and inhibits activin, a protein involved in a wide range of cellular processes, including the regulation of follicle-stimulating hormone (FSH) from the pituitary gland.
- The "344" isoform is the primary circulating form of Follistatin and is known for its high binding affinity for myostatin.
- Lee, S. J., & McPherron, A. C. (2001). Regulation of myostatin activity and muscle growth. Proceedings of the National Academy of Sciences, 98(16), 9306-9311.
- Haidet, A. M., et al. (2008). Long-term enhancement of skeletal muscle mass and strength by single gene administration of myostatin inhibitors. Proceedings of the National Academy of Sciences, 105(11), 4318-4322.
- Gilson, H., et al. (2009). Follistatin induces muscle hypertrophy through satellite cell proliferation and inhibition of both myostatin and activin. American Journal of Physiology-Endocrinology and Metabolism, 297(1), E157-E164.
- Sidis, Y., et al. (2001). Follistatin: a multifunctional regulatory protein. Endocrinology, 142(8), 3205-3208.